Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.49 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.48 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.48 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.48 |
| ▸ | RNASEL | Q05823 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25619503 | 0.83 | DNMT1 (0.56) | DNMT1DNMT3BADORA2AADORA2BADORA3 | |
| SCHEMBL25619482 | 0.83 | DNMT1 (0.56) | DNMT1DNMT3BADORA2AADORA2BADORA3 | |
| SCHEMBL6829244 | 0.82 | DNMT1 (0.48) | DNMT1DNMT3BADORA2AADORA2BADORA3 | |
| SCHEMBL2461485 | 0.76 | DNMT1 (0.63) | DNMT1DNMT3BADORA2AADORA2BADORA3 | |
| SCHEMBL8622533 | 0.76 | ADORA3 (0.78) | DNMT1DNMT3BADORA2AADORA2BADORA3 | |
| SCHEMBL29936666 | 0.76 | ADORA3 (0.78) | DNMT1DNMT3BADORA2AADORA2BADORA3 | |
| SCHEMBL28073065 | 0.75 | RNASEL (0.51) | DNMT1DNMT3BADORA2AADORA2BADORA3 | |
| SCHEMBL20009824 | 0.75 | DNMT1 (0.51) | DNMT1DNMT3BADORA2AADORA2BADORA3 | |
| SCHEMBL13769821 | 0.75 | ADORA3 (0.76) | DNMT1DNMT3BADORA2AADORA2BADORA3 | |
| 2-Methyladenosine SCHEMBL14075776 | 0.74 | LMNA (0.75) | ADORA2AADORA2BADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6740644-B2 | ADENOSINE DERIVATIVES, AGONISTS AT THE ADENOSINE A1 RECEPTOR | SMITHKLINE BEECHAM CORPORATION | 2004-05-25 | — | — | US | claimed |