Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27360380 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TDP1GAATHRBKDM4E | |
| SCHEMBL68271 | 0.81 | TDP1 (0.44) | ALDH1A1TDP1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL1979957 | 0.81 | CYP3A4 (0.43) | ALDH1A1TDP1GAATHRBKDM4E | |
| SCHEMBL8940830 | 0.78 | ESR1 (0.42) | ALDH1A1TDP1GAAKDM4EMEN1 | |
| SCHEMBL27492936 | 0.78 | SCN5A (0.38) | ALDH1A1TDP1GAATHRBKDM4E | |
| SCHEMBL10460608 | 0.77 | MAOA (0.43) | TDP1ESR1ESR2CA1CA12 | |
| SCHEMBL8293654 | 0.77 | TUBB1 (0.41) | ALDH1A1TDP1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL29421917 | 0.76 | MAOB (0.45) | ALDH1A1TDP1KDM4EMAPTESR1 | |
| SCHEMBL5141870 | 0.76 | MAOB (0.45) | ALDH1A1TDP1KDM4EMAPTESR1 | |
| SCHEMBL29403778 | 0.75 | TDP1 (0.52) | ALDH1A1TDP1GAATHRBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464247-B1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | OREAL (FR) | 2020-03-11 | — | — | EP | claimed |
| EP-1473025-B1 | Dyeing composition containing 2-chloro-6-methyl-3-aminophenol and an associative polymer | OREAL (FR) | 2012-03-28 | — | — | EP | claimed |
| US-7060112-B2 | Composition for the oxidation dyeing of keratinous fibers containing a laccase and dyeing method using this composition | L'OREAL (FR) | 2006-06-13 | — | — | US | claimed |
| US-20060021156-A1 | Composition for the oxidation dyeing of keratinous fibres containing a laccase and dyeing method using this composition | L'OREAL S.A. | 2006-02-02 | — | — | US | claimed |
| US-20040255401-A1 | Composition for the oxidation dyeing of keratinous fibres containing a laccase and dyeing method using this composition | L'OREAL | 2004-12-23 | — | — | US | claimed |
| CN-1440267-A | Oxidation dyeing composition for keratinous fibres comprising amphoteric polymer with fatty chain | OREAL (FR) | 2003-09-03 | — | — | CN | claimed |
| US-6599329-B1 | Composition for oxidation dyeing of keratinous fibers comprising colorant chosen from oxidation bases and their acid addition salts, coupler chosen from 2-amino-3-hydroxypyridine and its acid addition salts, and laccase enzyme | L'OREAL S.A. (FR) | 2003-07-29 | — | — | US | claimed |
| EP-0874615-B1 | COLORANTS FOR COLOURING KERATIN FIBRES | WELLA AG (DE) | 2003-04-02 | — | — | EP | claimed |
| US-6537328-B1 | Hair dye | L'OREAL S.A. (FR) | 2003-03-25 | — | — | US | claimed |
| CN-1262923-A | Composit for oxidation dyeing keratin fibre and dyeing method using said composit | OREAL (FR) | 2000-08-16 | — | — | CN | claimed |
| EP-0874615-A1 | COLORANTS FOR COLOURING KERATIN FIBRES | Wella Aktiengesellschaft (DE) | 1998-11-04 | — | — | EP | claimed |
| WO-1998019661-A1 | COLORANTS FOR COLOURING KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 1998-05-14 | — | — | WO | claimed |
| EP-0460128-A1 | AGENT AND PROCESS FOR THE OXIDATIVE DYEING OF HAIR. | WELLA AG (DE) | 1991-12-11 | — | — | EP | claimed |
| WO-1991009587-A1 | AGENT AND PROCESS FOR THE OXIDATIVE DYEING OF HAIR | WELLA AKTIENGESELLSCHAFT (DE) | 1991-07-11 | — | — | WO | claimed |
| CN-101137345-B | Novel hair coloring compositions for oxidative hair dyeing | PROCTER & GAMBLE | 2012-10-31 | — | — | CN | disclosed |
| US-8241370-B2 | Composition comprising an alkanolamine, a basic amino acid and a suitably selected additional alkaline agent | L'OREAL S.A. (FR) | 2012-08-14 | — | — | US | disclosed |
| US-8012220-B2 | Specific monocationic monochromophoric compounds of hydrazone type comprising a 2-, 4-pyridinium or 2-, 4-quinolinium unit, synthesis thereof, dye compositions containing them, and method for dyeing keratin fibres | L'OREAL S.A. (FR) | 2011-09-06 | — | — | US | disclosed |
| EP-0505528-A1 | HAIR COLORANT CONTAINING 1,4-BIS- (DIHYDROXYALKYL)AMINO]-ANTHRACHINONE AND NOVEL 1,4-BIS- (DIHYDROXYALKYL)AMINO)]-ANTHRACHINONES | Wella Aktiengesellschaft (DE) | 1992-09-30 | — | — | EP | disclosed |
| WO-1992006670-A1 | HAIR COLORANT CONTAINING 1,4-BIS-[(DIHYDROXYALKYL)AMINO]-ANTHRACHINONE AND NOVEL 1,4-BIS-[(DIHYDROXYALKYL)AMINO)]-ANTHRACHINONES | WELLA AKTIENGESELLSCHAFT (DE) | 1992-04-30 | — | — | WO | disclosed |
| EP-0395837-A1 | Oxidation hair dyes based on 4-aminophenol derivatives as well as new 4-aminophenol derivatives | Wella Aktiengesellschaft (DE) | 1990-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040255401-A1 | Composition for the oxidation dyeing of keratinous fibres containing a laccase and dyeing method using this composition | ALDH7A1, KRT18, LPO | ALDH1A1 170/4885TDP1 1433/4885GAA 1814/4885 |
| US-20060021156-A1 | Composition for the oxidation dyeing of keratinous fibres containing a laccase and dyeing method using this composition | TYR, KRT18, LPO | ALDH1A1 195/4885TDP1 2164/4885GAA 2271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.