Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5855467 | 0.87 | KMT2A (0.36) | KMT2AMEN1POLBATML3MBTL1 | |
| Hydrochloric Acid SCHEMBL5856658 | 0.79 | SIGMAR1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL6865136 | 0.79 | ACHE (0.39) | L3MBTL1BCHEACHE | |
| Hydrochloric Acid SCHEMBL6861247 | 0.76 | MEN1 (0.30) | KMT2AMEN1POLBATM | |
| Hydrochloric Acid SCHEMBL5853759 | 0.76 | MAPT (0.37) | KMT2AMEN1POLBPKM | |
| Hydrochloric Acid SCHEMBL7108766 | 0.75 | ALDH1A1 (0.40) | KMT2AMEN1POLBL3MBTL1BCHE | |
| Hydrochloric Acid SCHEMBL6827117 | 0.75 | POLB (0.34) | KMT2AMEN1POLBATML3MBTL1 | |
| Hydrochloric Acid SCHEMBL6702088 | 0.75 | KMT2A (0.34) | KMT2AMEN1POLBATM | |
| Hydrochloric Acid SCHEMBL7108565 | 0.75 | BCHE (0.41) | KMT2AMEN1BCHEACHE | |
| Hydrochloric Acid SCHEMBL5853050 | 0.74 | ALOX5 (0.38) | KMT2AMEN1L3MBTL1KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037989-B2 | Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-02 | — | — | US | disclosed |
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |
| US-20040242814-A1 | COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-02 | — | — | US | disclosed |