Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | KDM4B | O94953 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920288 | 0.76 | L3MBTL1 (0.53) | NR1I2KDM4BCHRM1TBXA2RADRA1A | |
| SCHEMBL6923871 | 0.73 | L3MBTL1 (0.54) | NR1I2KDM4BCHRM1TBXA2RADRA1A | |
| SCHEMBL6922814 | 0.72 | L3MBTL1 (0.57) | CYP1A2SMN1; SMN2HSP90AA1ATMHDAC4 | |
| SCHEMBL778084 | 0.71 | CYP11B2 (0.46) | TDP1LMNAKDM4ESMN1; SMN2HIF1A | |
| SCHEMBL6827359 | 0.70 | PGR (0.38) | NR1I2KDM4BCHRM1TBXA2RADRA1A | |
| SCHEMBL6827158 | 0.70 | KDM4E (0.34) | NR1I2KDM4BCHRM1TBXA2RADRA1A | |
| SCHEMBL6826222 | 0.70 | KCNH2 (0.38) | NR1I2KDM4BCHRM1TBXA2RADRA1A | |
| SCHEMBL6827260 | 0.70 | NOTUM (0.38) | NR1I2KDM4BCHRM1TBXA2RADRA1A | |
| SCHEMBL6823842 | 0.70 | PDE4D (0.41) | NR1I2KDM4BCHRM1TBXA2RADRA1A | |
| SCHEMBL6923841 | 0.70 | KAT7 (0.35) | NR1I2KDM4BCHRM1TBXA2RADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |