Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6923994 | 0.85 | PKM (0.53) | ALDH1A1POLBLMNAPKMRAB9A | |
| SCHEMBL3075154 | 0.84 | PKM (0.59) | ALDH1A1POLBLMNAPKMRAB9A | |
| SCHEMBL6925435 | 0.84 | ALDH1A1 (0.55) | ALDH1A1POLBLMNAPKMRAB9A | |
| SCHEMBL6920999 | 0.84 | PKLR (0.48) | ALDH1A1POLBLMNAL3MBTL1TDP1 | |
| SCHEMBL6929713 | 0.83 | ALDH1A1 (0.60) | ALDH1A1POLBLMNAPKMRAB9A | |
| SCHEMBL6827778 | 0.83 | ITGA1 (0.52) | ALDH1A1POLBLMNAKMT2A | |
| SCHEMBL3071479 | 0.82 | ALDH1A1 (0.52) | ALDH1A1POLBLMNAPKMKMT2A | |
| SCHEMBL6922338 | 0.81 | POLB (0.56) | ALDH1A1POLBLMNAPKMRAB9A | |
| SCHEMBL3069679 | 0.80 | ALDH1A1 (0.54) | ALDH1A1POLBLMNAPKMRAB9A | |
| SCHEMBL6831392 | 0.79 | ALDH1A1 (0.53) | ALDH1A1POLBLMNAPKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073619-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | claimed |