Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | UBE2N | P61088 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.49 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL683975 | 0.97 | LMNA (0.65) | LMNAMAPK1SMN1; SMN2POLBRXFP1 | |
| SCHEMBL683590 | 0.91 | SMN1; SMN2 (0.64) | LMNAMAPK1SMN1; SMN2POLBRXFP1 | |
| SCHEMBL682800 | 0.89 | RXFP1 (0.63) | LMNAMAPK1SMN1; SMN2POLBRXFP1 | |
| SCHEMBL684353 | 0.88 | SMN1; SMN2 (0.54) | LMNAMAPK1SMN1; SMN2POLBRXFP1 | |
| SCHEMBL684000 | 0.88 | SMN1; SMN2 (0.65) | LMNASMN1; SMN2POLBRXFP1ALDH1A1 | |
| SCHEMBL684337 | 0.88 | SMN1; SMN2 (0.68) | LMNAMAPK1SMN1; SMN2POLBRXFP1 | |
| SCHEMBL684003 | 0.87 | SMN1; SMN2 (0.68) | LMNAMAPK1SMN1; SMN2POLBRXFP1 | |
| SCHEMBL683589 | 0.86 | ALDH1A1 (0.54) | LMNASMN1; SMN2POLBRXFP1ALDH1A1 | |
| SCHEMBL682803 | 0.85 | SMN1; SMN2 (0.57) | LMNAMAPK1SMN1; SMN2POLBRXFP1 | |
| SCHEMBL684336 | 0.85 | RXFP1 (0.54) | LMNAMAPK1SMN1; SMN2POLBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | BRAINCELLS INC. (US) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | NGF, DCX, BDNF | LMNA 2155/4885MAPK1 470/4885SMN1; SMN2 907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.