Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.48 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL683975 | 0.88 | LMNA (0.65) | RXFP1SMN1; SMN2LMNAPOLBMAPK1 | |
| SCHEMBL682800 | 0.87 | RXFP1 (0.63) | RXFP1SMN1; SMN2LMNAPOLBMAPK1 | |
| SCHEMBL684000 | 0.87 | SMN1; SMN2 (0.65) | RXFP1SMN1; SMN2LMNAPOLBGAA | |
| SCHEMBL682806 | 0.85 | LMNA (0.62) | RXFP1SMN1; SMN2LMNAPOLBMAPK1 | |
| SCHEMBL684337 | 0.84 | SMN1; SMN2 (0.68) | RXFP1SMN1; SMN2LMNAPOLBMAPK1 | |
| SCHEMBL10897189 | 0.83 | HTR7 (0.55) | RXFP1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL682805 | 0.83 | HTR7 (0.53) | RXFP1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL683590 | 0.82 | SMN1; SMN2 (0.64) | RXFP1SMN1; SMN2LMNAPOLBMAPK1 | |
| SCHEMBL20561820 | 0.82 | LMNA (0.71) | RXFP1MAPTSMN1; SMN2LMNAPOLB | |
| SCHEMBL684003 | 0.82 | SMN1; SMN2 (0.68) | RXFP1SMN1; SMN2LMNAPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | BRAINCELLS INC. (US) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | NGF, DCX, BDNF | RXFP1 211/4885MAPT 1368/4885SMN1; SMN2 907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.