Triaziquone

Triaziquone

SCHEMBL6828224

CSC(C)S.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.40
TP53 P04637 1/20 0.38
MAPT P10636 1/20 0.38
STAT3 P40763 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
APAF1 O14727 2/20 0.34
TDP2 O95551 2/20 0.34
NSD2 O96028 2/20 0.34
HKDC1 Q2TB90 2/20 0.34
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
GALK1 P51570 1/20 0.33
BLM P54132 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33
NOD2 Q9HC29 1/20 0.33
ATG4B Q9Y4P1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL11545270 0.87 DNMT1 (0.42) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL6563614 0.86 MAPT (0.44) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL6828886 0.85 DNMT1 (0.36) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL8993238 0.84 DNMT1 (0.47) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL7088197 0.84 DNMT1 (0.47) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL7720256 0.83 DNMT1 (0.44) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL3100107 0.83 DNMT1 (0.44) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL112498 0.83 DNMT1 (0.39) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL1334390 0.82 DNMT1 (0.46) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL8303 0.82 DNMT1 (0.48) DNMT1TP53MAPTSTAT3HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190127508-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL OBTAINED FROM COMPOSITION, METHOD OF PRODUCING SAME MITSUI CHEMICALS, INC. (JP) 2019-05-02 US disclosed
EP-1448651-A1 HIGH IMPACT POLY(URETHANE UREA) POLYSULFIDES PPG Industries Ohio, Inc. (US) 2004-08-25 EP disclosed
WO-2003044070-A1 HIGH IMPACT POLY(URETHANE UREA) POLYSULFIDES PPG INDUSTRIES OHIO, INC. (US) 2003-05-30 WO disclosed
EP-1250369-A1 METHOD OF PREPARING AN OPTICAL POLYMERIZATE PPG Industries Ohio, Inc. (US) 2002-10-23 EP disclosed
WO-2001036507-A1 METHOD OF PREPARING AN OPTICAL POLYMERIZATE PPG INDUSTRIES OHIO, INC. (US) 2001-05-25 WO disclosed