Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CRHBP | P24387 | 3/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ATP4A | P20648 | 2/20 | 0.43 |
| ▸ | ATP4B | P51164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NMT1 | P30419 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828231 | 0.78 | NMT1 (0.40) | ALDH1A1ATP4AATP4BNMT1LMNA | |
| SCHEMBL6829068 | 0.70 | RAB9A (0.49) | MEN1KMT2ACRHBPCRHR2MAPT | |
| SCHEMBL6925018 | 0.70 | MEN1 (0.50) | MEN1KMT2ACRHBPCRHR2MAPT | |
| SCHEMBL19497012 | 0.67 | TAAR1 (0.53) | NMT1NOS1TAAR1 | |
| SCHEMBL2486885 | 0.66 | TAAR1 (0.58) | ALDH1A1NOS1TAAR1 | |
| SCHEMBL6510821 | 0.66 | CRHBP (0.80) | MEN1KMT2ACRHBPCRHR2MAPT | |
| SCHEMBL10501638 | 0.66 | MAPK1 (0.58) | MEN1KMT2ACRHBPCRHR2MAPT | |
| SCHEMBL6513368 | 0.65 | CRHBP (1.00) | MEN1KMT2ACRHBPCRHR2MAPT | |
| SCHEMBL14100109 | 0.65 | TAAR1 (0.56) | ALDH1A1ATP4AATP4BNOS1TAAR1 | |
| SCHEMBL3464184 | 0.64 | TAAR1 (0.67) | ALDH1A1NMT1NOS1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037166-A2 | THERAPEUTIC GUANIDINES | ISIS PHARMACEUTICALS, INC. (US) | 2004-05-06 | — | — | WO | disclosed |