Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 7/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.35 |
| ▸ | ATP4A | P20648 | 1/20 | 0.35 |
| ▸ | ATP4B | P51164 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2801059 | 0.81 | ALDH1A1 (0.48) | TAAR1ALDH1A1KDM4ELMNA | |
| SCHEMBL6828232 | 0.78 | MEN1 (0.47) | NMT1MCHR1TAAR1ALDH1A1LMNA | |
| SCHEMBL5923585 | 0.76 | AOC3 (0.46) | ALDH1A1LMNAAOC3 | |
| SCHEMBL5923052 | 0.74 | VCP (0.46) | ALDH1A1KDM4ELMNAHDAC1 | |
| SCHEMBL5923376 | 0.73 | EPHX2 (0.49) | ALDH1A1KDM4ELMNA | |
| SCHEMBL6829066 | 0.69 | IKBKB (0.35) | ALDH1A1KDM4ELMNAHDAC3HDAC1 | |
| SCHEMBL6925014 | 0.69 | TAAR1 (0.44) | TAAR1ALDH1A1KDM4ELMNA | |
| SCHEMBL19497012 | 0.68 | TAAR1 (0.53) | NMT1TAAR1AOC3 | |
| SCHEMBL5923306 | 0.68 | ALDH1A1 (0.48) | ALDH1A1KDM4ELMNA | |
| SCHEMBL2486885 | 0.67 | TAAR1 (0.58) | TAAR1ALDH1A1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037166-A2 | THERAPEUTIC GUANIDINES | ISIS PHARMACEUTICALS, INC. (US) | 2004-05-06 | — | — | WO | disclosed |