Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | CRHBP | P24387 | 4/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829068 | 0.80 | RAB9A (0.49) | MEN1KMT2ACRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL6925014 | 0.73 | TAAR1 (0.44) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL10501638 | 0.73 | MAPK1 (0.58) | MEN1KMT2ACRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL6828232 | 0.70 | MEN1 (0.47) | MEN1KMT2ACRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL10437265 | 0.70 | CAMK2D (0.53) | MEN1KMT2ACRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL10310269 | 0.69 | TAAR1 (0.55) | SMN1; SMN2RAB9AP2RX7TAAR1LMNA | |
| SCHEMBL4110628 | 0.68 | RAB9A (0.58) | MEN1KMT2ACRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL10498926 | 0.68 | CRHBP (0.83) | MEN1KMT2ACRHBPCRHR2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1623303 | 0.68 | TAAR1 (0.53) | SMN1; SMN2RAB9AP2RX7TAAR1LMNA | |
| SCHEMBL1180411 | 0.67 | HIF1A (0.67) | SMN1; SMN2MAPTRAB9AP2RX7TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037166-A2 | THERAPEUTIC GUANIDINES | ISIS PHARMACEUTICALS, INC. (US) | 2004-05-06 | — | — | WO | disclosed |