Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | CRHBP | P24387 | 5/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6925018 | 0.80 | MEN1 (0.50) | RAB9ACRHBPCRHR2MEN1KMT2A | |
| SCHEMBL6828232 | 0.70 | MEN1 (0.47) | RAB9ACRHBPCRHR2MEN1KMT2A | |
| SCHEMBL6509819 | 0.66 | RAB9A (1.00) | RAB9ACRHBPCRHR2MEN1KMT2A | |
| SCHEMBL10501638 | 0.66 | MAPK1 (0.58) | RAB9ACRHBPCRHR2MEN1KMT2A | |
| SCHEMBL10502867 | 0.66 | LMNA (0.57) | RAB9ACRHBPCRHR2MEN1KMT2A | |
| SCHEMBL28897071 | 0.64 | ALDH1A1 (0.45) | RAB9AMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL6513368 | 0.63 | CRHBP (1.00) | RAB9ACRHBPCRHR2MEN1KMT2A | |
| SCHEMBL11994138 | 0.63 | MC4R (0.43) | RAB9ACYP2D6ALDH1A1HSD17B10 | |
| SCHEMBL10498926 | 0.62 | CRHBP (0.83) | RAB9ACRHBPCRHR2MEN1KMT2A | |
| SCHEMBL10388189 | 0.61 | KMT2A (0.66) | RAB9ACRHBPCRHR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037166-A2 | THERAPEUTIC GUANIDINES | ISIS PHARMACEUTICALS, INC. (US) | 2004-05-06 | — | — | WO | disclosed |