Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6825954 | 0.84 | L3MBTL1 (0.51) | ALDH1A1HPGDMAPTMRGPRX4KMT2A | |
| SCHEMBL6829671 | 0.77 | KMT2A (0.54) | ALDH1A1HPGDMAPTMRGPRX4KMT2A | |
| SCHEMBL6829218 | 0.77 | KMT2A (0.48) | ALDH1A1HPGDMAPTMRGPRX4KMT2A | |
| SCHEMBL7129657 | 0.77 | ALDH1A1 (0.48) | ALDH1A1HPGDMAPTMRGPRX4KMT2A | |
| SCHEMBL6922276 | 0.76 | LMNA (0.57) | ALDH1A1HPGDMAPTMRGPRX4KMT2A | |
| SCHEMBL7129725 | 0.75 | MRGPRX4 (0.54) | MAPTMRGPRX4KMT2AMEN1L3MBTL1 | |
| SCHEMBL29130678 | 0.74 | LMNA (0.49) | ALDH1A1HPGDMAPTMRGPRX4KMT2A | |
| SCHEMBL6829495 | 0.73 | MAOA (0.43) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL11392272 | 0.71 | KMT2A (0.55) | HPGDMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13949073 | 0.70 | ALDH1A1 (0.53) | ALDH1A1HPGDMAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |