Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826044 | 0.82 | MAPT (0.56) | ALDH1A1TSHRLMNASMN1; SMN2MAPT | |
| SCHEMBL6924355 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TSHRSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL6923000 | 0.77 | ALDH1A1 (0.42) | ALDH1A1TSHRLMNASMN1; SMN2MAPT | |
| SCHEMBL6826138 | 0.71 | ALDH1A1 (0.61) | ALDH1A1TSHRLMNASMN1; SMN2MAPT | |
| SCHEMBL6828867 | 0.71 | ALDH1A1 (0.38) | ALDH1A1TSHRLMNASMN1; SMN2MAPT | |
| SCHEMBL20569271 | 0.71 | ALDH1A1 (0.62) | ALDH1A1TSHRLMNASMN1; SMN2MAPT | |
| SCHEMBL1200890 | 0.71 | ALDH1A1 (0.42) | ALDH1A1TSHRLMNASMN1; SMN2MAPT | |
| SCHEMBL31121618 | 0.70 | ALDH1A1 (0.61) | ALDH1A1TSHRLMNASMN1; SMN2POLB | |
| SCHEMBL7981961 | 0.70 | LMNA (0.44) | ALDH1A1LMNASMN1; SMN2MAPTRAB9A | |
| SCHEMBL11292466 | 0.70 | L3MBTL1 (0.44) | ALDH1A1LMNASMN1; SMN2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |