Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.66 |
| ▸ | RAB9A | P51151 | 8/20 | 0.66 |
| ▸ | NPC1 | O15118 | 7/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.66 |
| ▸ | LMNA | P02545 | 6/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829093 | 0.87 | LMNA (0.55) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6829213 | 0.81 | RAB9A (0.57) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7121858 | 0.77 | ALDH1A1 (0.66) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6829038 | 0.77 | RAB9A (0.60) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6829050 | 0.76 | NPC1 (0.56) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6920464 | 0.75 | GAA (0.67) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6427130 | 0.75 | MEN1 (1.00) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17582660 | 0.73 | MEN1 (0.56) | MAPTALDH1A1RAB9ANPC1LMNA | |
| SCHEMBL6633618 | 0.72 | KMT2A (0.89) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6920663 | 0.71 | ALDH1A1 (0.45) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |