Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.58 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829050 | 0.86 | NPC1 (0.56) | RAB9ASMN1; SMN2MAPTHTTKCNH2 | |
| SCHEMBL6829093 | 0.83 | LMNA (0.55) | RAB9ASMN1; SMN2MAPTHTTMEN1 | |
| SCHEMBL6829213 | 0.83 | RAB9A (0.57) | RAB9ASMN1; SMN2MAPTHTTMEN1 | |
| SCHEMBL6829037 | 0.77 | MAPT (0.66) | RAB9ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL7129347 | 0.76 | RAB9A (0.62) | RAB9ASMN1; SMN2MAPTHTTKCNH2 | |
| SCHEMBL6829504 | 0.74 | SMN1; SMN2 (0.55) | RAB9ASMN1; SMN2MAPTKCNH2SCN10A | |
| SCHEMBL13219526 | 0.74 | JAK2 (1.00) | RAB9ASMN1; SMN2MAPTHTTJAK2 | |
| SCHEMBL6920464 | 0.72 | GAA (0.67) | RAB9ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL259427 | 0.72 | KCNK3 (0.82) | RAB9ASMN1; SMN2MAPTHTTMEN1 | |
| SCHEMBL17582660 | 0.70 | MEN1 (0.56) | RAB9AMAPTHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |