Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KLK7 | P49862 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 9/20 | 0.50 |
| ▸ | RAB9A | P51151 | 9/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829037 | 0.87 | MAPT (0.66) | LMNATP53ALDH1A1HPGDKLK7 | |
| SCHEMBL6829213 | 0.85 | RAB9A (0.57) | LMNATP53ALDH1A1HPGDKLK7 | |
| SCHEMBL6829038 | 0.83 | RAB9A (0.60) | LMNATP53ALDH1A1HPGDMAPT | |
| SCHEMBL17664665 | 0.78 | KLK7 (0.89) | LMNATP53ALDH1A1HPGDKLK7 | |
| SCHEMBL6831239 | 0.77 | LMNA (0.56) | LMNATP53ALDH1A1HPGDGAA | |
| SCHEMBL6829050 | 0.77 | NPC1 (0.56) | LMNATP53ALDH1A1HPGDGAA | |
| SCHEMBL18180861 | 0.75 | RAB9A (0.70) | LMNATP53ALDH1A1HPGDKLK7 | |
| SCHEMBL17582660 | 0.74 | MEN1 (0.56) | LMNAALDH1A1HPGDGAAKDM4E | |
| SCHEMBL6920464 | 0.73 | GAA (0.67) | TP53ALDH1A1HPGDGAAKDM4E | |
| SCHEMBL18027751 | 0.73 | ALDH1A1 (0.65) | LMNATP53ALDH1A1HPGDKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |