Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 1/20 | 0.56 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.53 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL800299 | 0.87 | HSP90B1 (0.58) | HINT1HSP90B1ADORA2AADORA2BNT5E | |
| SCHEMBL226039 | 0.85 | AHCY (0.63) | HSP90B1ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL1275031 | 0.81 | HINT1 (0.58) | HINT1NT5E | |
| SCHEMBL18954813 | 0.81 | HINT1 (0.44) | HINT1ADORA2AADORA2BNT5EADORA3 | |
| SCHEMBL25619503 | 0.81 | DNMT1 (0.56) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL25619482 | 0.81 | DNMT1 (0.56) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL6829146 | 0.81 | HINT1 (0.67) | HINT1ADORA2AADORA2BNT5EADORA3 | |
| SCHEMBL19843948 | 0.80 | ADORA3 (0.77) | HINT1HSP90B1ADORA2AADORA2BNT5E | |
| SCHEMBL4452559 | 0.80 | ADORA3 (0.77) | HINT1HSP90B1ADORA2AADORA2BNT5E | |
| SCHEMBL4452551 | 0.80 | ADORA3 (0.77) | HINT1HSP90B1ADORA2AADORA2BNT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040214198-A1 | Allele-targeted RNA interference | UNIVERSITY OF MASSACHUSETTS | 2004-10-28 | — | — | US | disclosed |
| WO-2004046324-A2 | ALLELE-TARGETED RNA INTERFERENCE | UNIVERSITY OF MASSACHUSETTS (US) | 2004-06-03 | — | — | WO | disclosed |