Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829064 | 0.79 | CYP3A4 (0.40) | KDM4EMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6919722 | 0.73 | TP53 (0.38) | KDM4EMEN1CYP1A2CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL17675148 | 0.73 | EDNRB (0.35) | MEN1CYP2C9KMT2AALDH1A1 | |
| SCHEMBL4708203 | 0.73 | HTR2A (0.34) | KMT2A | |
| SCHEMBL3696570 | 0.71 | ALDH1A1 (0.44) | KDM4ECYP3A4HPGDHSD17B10THRB | |
| SCHEMBL19647091 | 0.71 | CXCR5 (0.37) | MEN1KMT2ATHRBTDP1ALDH1A1 | |
| SCHEMBL1325109 | 0.71 | THRB (0.38) | THRBTDP1LMNABLMGAA | |
| SCHEMBL3753675 | 0.71 | OPRM1 (0.33) | KMT2A | |
| SCHEMBL18993896 | 0.68 | MME (0.43) | MEN1KMT2ATP53CXCR5 | |
| SCHEMBL18986930 | 0.68 | THRB (0.36) | THRBTDP1LMNABLMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096774-A1 | ACYL ISOINDOLINE DERIVATIVES AND ACYL ISOQUINOLINE DERIVATIVES AS ANTI-VIRAL AGENTS | GLAXO GROUP LIMITED (GB) | 2004-11-11 | — | — | WO | disclosed |