Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CXCR5 | P32302 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830859 | 0.79 | LMNA (0.40) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL7038616 | 0.78 | ALDH1A1 (0.35) | MEN1KMT2ACYP2C19CXCR5GAA | |
| SCHEMBL18993896 | 0.74 | MME (0.43) | TP53MEN1KMT2ACXCR5MME | |
| SCHEMBL6829176 | 0.73 | KDM4E (0.35) | TP53MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL5334825 | 0.71 | ALDH1A1 (0.40) | GAAMAPTHDAC9 | |
| Hydrochloric Acid SCHEMBL2084296 | 0.70 | ALDH1A1 (0.42) | GAAMAPTHDAC9 | |
| SCHEMBL3733923 | 0.68 | HDAC9 (0.38) | CXCR5GAAMAPTMMEHDAC9 | |
| SCHEMBL19647091 | 0.68 | CXCR5 (0.37) | TP53MEN1KMT2ACXCR5 | |
| SCHEMBL26605081 | 0.65 | HDAC9 (0.41) | CXCR5GRM7MMEHDAC9 | |
| SCHEMBL30868729 | 0.65 | MME (0.37) | MEN1KMT2AMMEHDAC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096774-A1 | ACYL ISOINDOLINE DERIVATIVES AND ACYL ISOQUINOLINE DERIVATIVES AS ANTI-VIRAL AGENTS | GLAXO GROUP LIMITED (GB) | 2004-11-11 | — | — | WO | disclosed |