Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.57 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830687 | 0.91 | HTR6 (0.57) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL6924345 | 0.87 | HTR6 (0.59) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL6826181 | 0.83 | HTR6 (0.48) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL6829699 | 0.80 | HTR6 (0.60) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL6925862 | 0.79 | HRH3 (0.50) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL6829836 | 0.76 | HTR6 (0.60) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL6829301 | 0.76 | NOD2 (0.60) | HTR6CYP3A4CYP2D6NOD2NOD1 | |
| Hydrochloric Acid SCHEMBL6826441 | 0.76 | HTR6 (0.59) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL4794912 | 0.75 | NOD1 (0.63) | HTR6NOD2NOD1 | |
| SCHEMBL6830157 | 0.75 | HTR6 (0.59) | HTR6CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108671-A1 | SUBSTITUTED INDOLES WITH SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-12-16 | — | — | WO | disclosed |