SCHEMBL6829573

SCHEMBL6829573

O=Cc1ccc(N2CCSCC2)cc1

nearest known ligand 0.68

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.68
TRIM33 Q9UPN9 1/20 0.68
ALDH1A1 P00352 5/20 0.66
KDM4E B2RXH2 2/20 0.66
SMN1; SMN2 Q16637 2/20 0.66
MAPT P10636 2/20 0.53
APP P05067 1/20 0.48
LGMN Q99538 2/20 0.46
AKR1C3 P42330 1/20 0.44
MAOB P27338 1/20 0.42
THRB P10828 1/20 0.41
PTGS2 P35354 3/20 0.41
ACHE P22303 1/20 0.40
KCNJ1 P48048 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2561698 0.85 TRIM24 (0.83) TRIM24TRIM33ALDH1A1KDM4ESMN1; SMN2
SCHEMBL3077544 0.85 TRIM24 (0.83) TRIM24TRIM33ALDH1A1KDM4ESMN1; SMN2
SCHEMBL7180854 0.81 TRIM24 (0.91) TRIM24TRIM33ALDH1A1KDM4ESMN1; SMN2
SCHEMBL253732 0.81 TRIM24 (1.00) TRIM24TRIM33ALDH1A1KDM4ESMN1; SMN2
SCHEMBL160596 0.79 ALDH1A1 (1.00) TRIM24TRIM33ALDH1A1KDM4ESMN1; SMN2
SCHEMBL896372 0.79 ALDH1A1 (1.00) TRIM24TRIM33ALDH1A1KDM4ESMN1; SMN2
SCHEMBL1443539 0.78 TRIM24 (0.70) TRIM24TRIM33ALDH1A1KDM4ESMN1; SMN2
SCHEMBL211336 0.78 TRIM24 (0.70) TRIM24TRIM33ALDH1A1KDM4ESMN1; SMN2
SCHEMBL23117380 0.76 TRIM24 (0.68) TRIM24TRIM33ALDH1A1KDM4ESMN1; SMN2
SCHEMBL559578 0.76 TRIM24 (0.68) TRIM24TRIM33ALDH1A1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119118969-B Hypochlorous acid fluorescent probe and preparation method and application thereof 山东理工大学 2025-03-28 CN claimed
CN-118812477-B Huang Tongji quenching type fluorescent probe for specifically detecting hypochlorous acid as well as preparation method and application thereof 南京林业大学 2024-12-27 CN claimed
CN-119118969-A Quick high-selectivity hypochlorous acid fluorescent probe and preparation method and application thereof 山东理工大学 2024-12-13 CN claimed
CN-119118958-A Near infrared fluorescent probe for detecting hypochlorous acid and preparation method and application thereof 新乡医学院 2024-12-13 CN claimed
CN-118812477-A Huang Tongji quenching type fluorescent probe for specifically detecting hypochlorous acid as well as preparation method and application thereof 南京林业大学 2024-10-22 CN claimed
CN-119118969-B Hypochlorous acid fluorescent probe and preparation method and application thereof 山东理工大学 2025-03-28 CN disclosed
CN-118812477-B Huang Tongji quenching type fluorescent probe for specifically detecting hypochlorous acid as well as preparation method and application thereof 南京林业大学 2024-12-27 CN disclosed
CN-118812477-B Huang Tongji quenching type fluorescent probe for specifically detecting hypochlorous acid as well as preparation method and application thereof 南京林业大学 2024-12-27 CN disclosed
CN-119118969-A Quick high-selectivity hypochlorous acid fluorescent probe and preparation method and application thereof 山东理工大学 2024-12-13 CN disclosed
CN-119118958-A Near infrared fluorescent probe for detecting hypochlorous acid and preparation method and application thereof 新乡医学院 2024-12-13 CN disclosed
CN-118812477-A Huang Tongji quenching type fluorescent probe for specifically detecting hypochlorous acid as well as preparation method and application thereof 南京林业大学 2024-10-22 CN disclosed
CN-118812477-A Huang Tongji quenching type fluorescent probe for specifically detecting hypochlorous acid as well as preparation method and application thereof 南京林业大学 2024-10-22 CN disclosed
US-20130210813-A1 Male Contraceptive Compositions and Methods of Use DANA-FARBER CANCER INSTITUTE, INC. 2013-08-15 US disclosed
US-20130210813-A1 Male Contraceptive Compositions and Methods of Use DANA-FARBER CANCER INSTITUTE, INC. 2013-08-15 US disclosed
US-20130184264-A1 Compositions And Methods For Treating Neoplasia, Inflammatory Disease And Other Disorders NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2013-07-18 US disclosed
US-20120237475-A1 Novel Inhibitors PROBIODRUG AG (DE) 2012-09-20 US disclosed
WO-2012123563-A1 BENZ IMIDAZOLE DERIVATIVES AS INHIBITORS OF GLUTAMINYL CYCLASE PROBIODRUG AG (DE) 2012-09-20 WO disclosed
WO-2004108723-A1 4,5-DIHYDRO-IMIDAZO[4,5,1-II]QUINOLIN-6-ONES AS PARP INHIBITORS ALTANA PHARMA AG (DE) 2004-12-16 WO disclosed
US-6288061-B1 INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS WELFIDE CORPORATION (JP) 2001-09-11 US disclosed
EP-0011092-A1 Alpha-aminophenylacetic acid derivatives for use in the treatment of inflammations and novel alpha-aminophenylacetic acid derivatives BAYER AG (DE) 1980-05-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130210813-A1 Male Contraceptive Compositions and Methods of Use SHBG, CYP19A1, CYP17A1 TRIM24 3585/4885TRIM33 2219/4885ALDH1A1 1692/4885
US-20130184264-A1 Compositions And Methods For Treating Neoplasia, Inflammatory Disease And Other Disorders BRPF3, EP300, BRD3 TRIM24 729/4885TRIM33 322/4885ALDH1A1 3670/4885
US-20120237475-A1 Novel Inhibitors GLS, NQO2, GLS2 TRIM24 2890/4885TRIM33 3632/4885ALDH1A1 1025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.