SCHEMBL68296

SCHEMBL68296

COC(=O)c1ccc2cccc(C(=O)OC)c2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.51
ALDH1A1 P00352 3/20 0.51
KDM4E B2RXH2 3/20 0.51
HPGD P15428 2/20 0.51
HSD17B10 Q99714 2/20 0.51
GLA P06280 1/20 0.51
GAA P10253 1/20 0.51
CASP1 P29466 1/20 0.51
CASP7 P55210 1/20 0.51
ATM Q13315 1/20 0.51
PLAU P00749 3/20 0.50
NQO2 P16083 1/20 0.50
MTNR1A P48039 1/20 0.50
LCK P06239 1/20 0.50
PTPN11 Q06124 2/20 0.49
ALOX15 P16050 1/20 0.49
HTT P42858 1/20 0.49
SLC6A2 P23975 1/20 0.49
SLC6A4 P31645 1/20 0.49
SLC6A3 Q01959 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29576093 1.00 MAPT (0.51) MAPTALDH1A1KDM4EHPGDHSD17B10
SCHEMBL28311980 0.90 PLA2G2D (0.60) MAPTALDH1A1KDM4EHPGDHSD17B10
SCHEMBL30362194 0.89 NQO2 (0.47) MAPTALDH1A1KDM4EHPGDHSD17B10
SCHEMBL23909536 0.89 NQO2 (0.47) MAPTALDH1A1KDM4EHPGDHSD17B10
SCHEMBL23909555 0.89 PLAU (0.54) MAPTALDH1A1KDM4EHPGDHSD17B10
SCHEMBL23909574 0.89 PLAU (0.47) MAPTALDH1A1KDM4EHPGDHSD17B10
SCHEMBL23909601 0.89 PLAU (0.54) MAPTALDH1A1KDM4EHPGDHSD17B10
SCHEMBL30362183 0.89 PLAU (0.54) MAPTALDH1A1KDM4EHPGDHSD17B10
SCHEMBL26886714 0.88 MTNR1A (0.59) MAPTALDH1A1KDM4EPLAUNQO2
SCHEMBL69179 0.87 LCK (0.58) MAPTALDH1A1KDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115777000-A Amorphous copolyester resins for industrial coatings and method for coating metal surfaces using such coating compositions 波士胶公司 2023-03-10 CN claimed
CN-117480216-A Thermoplastic resin composition and molded article produced from the same 乐天化学株式会社 2024-01-30 CN disclosed
CN-115777000-A Amorphous copolyester resins for industrial coatings and method for coating metal surfaces using such coating compositions 波士胶公司 2023-03-10 CN disclosed
CN-112771109-B Thermoplastic resin composition and molded article produced therefrom 乐天化学株式会社 2023-01-31 CN disclosed
CN-111344340-B Thermoplastic resin composition and molded product made therefrom 乐天化学株式会社 2022-07-29 CN disclosed
CN-114641535-A Thermoplastic resin composition and molded article produced therefrom 乐天化学株式会社 2022-06-17 CN disclosed
CN-114466894-A Thermoplastic resin composition and molded article produced therefrom 乐天化学株式会社 2022-05-10 CN disclosed
CN-110114414-B Thermoplastic resin composition for laser direct structuring process and molded article produced therefrom 乐天尖端材料株式会社 2021-11-12 CN disclosed
CN-113056521-A Thermoplastic resin composition and molded article therefrom 乐天化学株式会社 2021-06-29 CN disclosed
CN-112771109-A Thermoplastic resin composition and molded article produced therefrom 乐天化学株式会社 2021-05-07 CN disclosed
CN-112442260-A Thermoplastic resin composition and articles produced therefrom 乐天化学株式会社 2021-03-05 CN disclosed
CN-107531987-B Polycarbonate resin composition and molded article using same 乐天尖端材料株式会社 2020-12-18 CN disclosed
CN-111344340-A Thermoplastic resin composition and molded product made therefrom 乐天化学株式会社 2020-06-26 CN disclosed
CN-110114414-A Thermoplastic resin composition for laser direct forming technique and the mechanograph by its production 乐天尖端材料株式会社 2019-08-09 CN disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 MAPT 1923/4885ALDH1A1 1882/4885KDM4E 717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.