Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 2/20 | 0.35 |
| ▸ | ALPI | P09923 | 2/20 | 0.35 |
| ▸ | GSR | P00390 | 2/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28649069 | 0.81 | TXNRD1 (0.42) | NFE2L2ALPLALPITXNRD1S1PR4 | |
| SCHEMBL6826700 | 0.78 | ALDH1A1 (0.39) | S1PR4ALDH1A1LMNAHTTKMT2A | |
| SCHEMBL28644545 | 0.74 | NFE2L2 (0.42) | NFE2L2LMNA | |
| SCHEMBL16094497 | 0.73 | ALDH1A1 (0.41) | S1PR4TSHRMAPTALDH1A1 | |
| SCHEMBL28737017 | 0.72 | GSR (0.33) | ALPLALPIGSRTXNRD1MAPT | |
| SCHEMBL5431429 | 0.70 | ALDH1A1 (0.44) | NFE2L2S1PR4MAPTCA2CA12 | |
| SCHEMBL10582499 | 0.68 | NFE2L2 (0.45) | NFE2L2MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL28552196 | 0.68 | ALPI (0.40) | ALPLALPICA2CA12ALDH1A1 | |
| SCHEMBL27716170 | 0.68 | MAPT (0.46) | ALPLALPIMAPTALDH1A1 | |
| SCHEMBL27826373 | 0.67 | CFD (0.44) | TSHRMAPTCA12ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |