Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1237692 | 0.84 | TSHR (0.44) | TSHRMEN1KMT2AALDH1A1PIN1 | |
| SCHEMBL5778129 | 0.79 | KMT2A (0.44) | TSHRKMT2AALDH1A1GAANPC1 | |
| SCHEMBL9621660 | 0.74 | ALDH1A1 (0.44) | TSHRALDH1A1GAAMAPTLMNA | |
| SCHEMBL6931923 | 0.74 | NPC1 (0.42) | TSHRMEN1KMT2AALDH1A1PIN1 | |
| SCHEMBL918997 | 0.73 | ORAI1 (0.42) | TSHRALDH1A1MAPTLMNAPOLB | |
| Phenol SCHEMBL5132995 | 0.72 | ALDH1A1 (0.56) | TSHRMEN1KMT2AALDH1A1PIN1 | |
| Benzene SCHEMBL27658560 | 0.72 | ALDH1A1 (0.81) | TSHRMEN1KMT2AALDH1A1PIN1 | |
| O-Xylene SCHEMBL19859039 | 0.71 | ALDH1A1 (0.62) | TSHRMEN1KMT2AALDH1A1PIN1 | |
| SCHEMBL37520 | 0.71 | MAPT (0.56) | TSHRMEN1KMT2AALDH1A1PIN1 | |
| Diethyl Pyrocarbonate SCHEMBL27970756 | 0.71 | SOAT1 (0.62) | TSHRMEN1KMT2AALDH1A1PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433364-A | Hydrogen bond organic molecular framework material HOF-NBDA and preparation method and application thereof | 中国科学院福建物质结构研究所 | 2022-12-06 | — | — | CN | claimed |
| CN-115433364-B | Hydrogen bond organic molecular framework material HOF-NBDA, and preparation method and application thereof | 中国科学院福建物质结构研究所 | 2023-09-08 | — | — | CN | disclosed |
| CN-115433364-A | Hydrogen bond organic molecular framework material HOF-NBDA and preparation method and application thereof | 中国科学院福建物质结构研究所 | 2022-12-06 | — | — | CN | disclosed |
| EP-3790883-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | Aprinoia Therapeutics Inc. (TW) | 2021-03-17 | — | — | EP | disclosed |
| WO-2019214681-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | APRINOIA THERAPEUTICS INC. (CN) | 2019-11-14 | — | — | WO | disclosed |
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |