Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829989 | 0.84 | TSHR (0.46) | TSHRMEN1KMT2AALDH1A1PIN1 | |
| SCHEMBL2359233 | 0.83 | TSHR (0.50) | TSHRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL1237722 | 0.81 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL28664851 | 0.81 | TRPV6 (0.44) | TSHRALDH1A1LMNAL3MBTL1 | |
| SCHEMBL1237453 | 0.79 | KMT2A (0.42) | TSHRKMT2AALDH1A1MAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL3987325 | 0.78 | KMT2A (0.41) | TSHRKMT2AALDH1A1MAPTHSD17B10 | |
| SCHEMBL4508305 | 0.78 | ELANE (0.42) | TSHRALDH1A1GAAMAPTLMNA | |
| SCHEMBL6931923 | 0.76 | NPC1 (0.42) | TSHRMEN1KMT2AALDH1A1PIN1 | |
| SCHEMBL18424371 | 0.75 | CYP2C19 (0.39) | TSHRMEN1KMT2AALDH1A1GAA | |
| SCHEMBL651370 | 0.75 | ORAI1 (0.42) | TSHRALDH1A1GAAMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433364-A | Hydrogen bond organic molecular framework material HOF-NBDA and preparation method and application thereof | 中国科学院福建物质结构研究所 | 2022-12-06 | — | — | CN | claimed |
| US-9162999-B2 | Catalytic conversion of cellulose to fuels and chemicals using boronic acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-10-20 | — | — | US | claimed |
| EP-2059227-A2 | POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY | Aeris Therapeutics, Inc. (US) | 2009-05-20 | — | — | EP | claimed |
| WO-2008039827-A2 | POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY | AERIS THERAPEUTICS, INC. (US) | 2008-04-03 | — | — | WO | claimed |
| CN-115433364-B | Hydrogen bond organic molecular framework material HOF-NBDA, and preparation method and application thereof | 中国科学院福建物质结构研究所 | 2023-09-08 | — | — | CN | disclosed |
| US-20230181462-A1 | Dynamic Covalent Hydrogels, Precursors Thereof and Uses Thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-06-15 | — | — | US | disclosed |
| EP-4118136-A1 | DYNAMIC COVALENT HYDROGELS, PRECURSORS THEREOF AND USES THEREOF | Centre National de la Recherche Scientifique (CNRS) (FR) | 2023-01-18 | — | — | EP | disclosed |
| CN-115433364-A | Hydrogen bond organic molecular framework material HOF-NBDA and preparation method and application thereof | 中国科学院福建物质结构研究所 | 2022-12-06 | — | — | CN | disclosed |
| CN-114262340-A | Preparation method of aminophenylboronic acid | 蚌埠中实化学技术有限公司 | 2022-04-01 | — | — | CN | disclosed |
| EP-3790883-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | Aprinoia Therapeutics Inc. (TW) | 2021-03-17 | — | — | EP | disclosed |
| WO-2019214681-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | APRINOIA THERAPEUTICS INC. (CN) | 2019-11-14 | — | — | WO | disclosed |
| US-10032986-B2 | Polycyclic compound and organic light emitting device including the same | LG CHEM, LTD. (KR) | 2018-07-24 | — | — | US | disclosed |
| US-20070287705-A1 | Crf Receptor Antagonists and Methods Relating Thereto | NEUROCRINE BIOSCIENCES, INC. | 2007-12-13 | — | — | US | disclosed |
| WO-2007130468-A2 | PYRIDO [2, 3-B] PYRAZINE AND [1, 8] -NAPHTHYRIDINE DERIVATIVES AS ALK AND C-MET INHIBITORS | CEPHALON, INC. (US) | 2007-11-15 | — | — | WO | disclosed |
| EP-1815206-A1 | COMPOUNDS FOR NONSENSE SUPPRESSION, AND METHODS FOR THEIR USE | PTC Therapeutics, Inc. (US) | 2007-08-08 | — | — | EP | disclosed |
| WO-2007070045-A1 | PREPARATION OF SUBSTITUTED BRIDGED INDENYL AND RELATED LIGANDS | EXXONMOBIL CHEMICAL PATENTS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |
| EP-1697374-A1 | CRF RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | SB Pharmco Puerto Rico Inc. (PR) | 2006-09-06 | — | — | EP | disclosed |
| WO-2006044456-A1 | COMPOUNDS FOR NONSENSE SUPPRESSION, AND METHODS FOR THEIR USE | PTC THERAPEUTICS, INC. (US) | 2006-04-27 | — | — | WO | disclosed |
| WO-2005063755-A1 | CRF RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | SB PHARMCO PUERTO RICO INC (US) | 2005-07-14 | — | — | WO | disclosed |
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287705-A1 | Crf Receptor Antagonists and Methods Relating Thereto | CRHR1, CRHR2, CRH | TSHR 220/4885MEN1 1737/4885KMT2A 3165/4885 |
| US-10032986-B2 | Polycyclic compound and organic light emitting device including the same | PPOX, CRY1, CRY2 | TSHR 4236/4885MEN1 643/4885KMT2A 170/4885 |
| US-20230181462-A1 | Dynamic Covalent Hydrogels, Precursors Thereof and Uses Thereof | CDC37, ILK, PTMS | TSHR 4380/4885MEN1 4666/4885KMT2A 2860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.