Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GGT1 | P19440 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13475992 | 0.82 | ORAI1 (0.48) | ALDH1A1HSD17B10KDM4ETSHRNAPRT | |
| SCHEMBL918997 | 0.81 | ORAI1 (0.42) | ALDH1A1HSD17B10TSHRNAPRTBLM | |
| SCHEMBL1712461 | 0.81 | ELANE (0.46) | ALDH1A1HSD17B10KDM4ETSHRNAPRT | |
| SCHEMBL651370 | 0.80 | ORAI1 (0.42) | ALDH1A1HSD17B10KDM4ETSHRNAPRT | |
| SCHEMBL5778129 | 0.78 | KMT2A (0.44) | ALDH1A1HSD17B10KDM4ETSHRNAPRT | |
| SCHEMBL384013 | 0.77 | ORAI1 (0.42) | ALDH1A1TSHRNAPRTLMNACYP1A2 | |
| SCHEMBL6829989 | 0.74 | TSHR (0.46) | ALDH1A1HSD17B10TSHRLMNAGAA | |
| SCHEMBL5943883 | 0.72 | NPC1 (0.50) | ALDH1A1TSHRESR1TDP1LMNA | |
| SCHEMBL3034251 | 0.71 | TSHR (0.36) | ALDH1A1HSD17B10TSHRBLMTDP1 | |
| SCHEMBL4768280 | 0.71 | SMN1; SMN2 (0.50) | ALDH1A1HSD17B10TSHRNAPRTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266105-B1 | PRODUCTION OF CERAMIC MATERIALS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-29 | — | — | EP | disclosed |
| US-4861735-A | Production of ceramic materials | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-08-29 | — | — | US | disclosed |
| EP-0266105-A2 | Production of ceramic materials | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-05-04 | — | — | EP | disclosed |