Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830780 | 0.84 | ALDH1A1 (0.43) | NPC1RAB9ASMN1; SMN2TAAR1TMEM97 | |
| SCHEMBL6830387 | 0.79 | RAB9A (0.53) | NPC1RAB9ASMN1; SMN2TAAR1TMEM97 | |
| SCHEMBL6830383 | 0.76 | MMP2 (0.40) | NPC1ALDH1A1MAPTKDM4EUSP2 | |
| SCHEMBL6830393 | 0.76 | MEN1 (0.53) | NPC1RAB9ASMN1; SMN2TAAR1TMEM97 | |
| SCHEMBL6827975 | 0.74 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2TAAR1TMEM97 | |
| SCHEMBL6962971 | 0.70 | SMN1; SMN2 (0.89) | NPC1RAB9ASMN1; SMN2TAAR1TMEM97 | |
| SCHEMBL11024162 | 0.70 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2TAAR1TMEM97 | |
| SCHEMBL6830779 | 0.68 | PPARG (0.49) | NPC1RAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL27731771 | 0.67 | MEN1 (0.61) | NPC1RAB9ASMN1; SMN2TAAR1ALDH1A1 | |
| SCHEMBL6625969 | 0.67 | EPHX1 (0.69) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074238-A1 | PHENETHYLAMINO SULFAMIC ACIDS | THE PROCTER & GAMBLE COMPANY (US) | 2004-09-02 | — | — | WO | disclosed |