Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | RPA1 | P27694 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6353699 | 0.85 | RAB9A (0.56) | SMN1; SMN2LMNARAB9ANPC1TSHR | |
| SCHEMBL6353696 | 0.85 | PTGES (0.56) | SMN1; SMN2LMNAHTTRAB9ANPC1 | |
| SCHEMBL6833237 | 0.84 | RAB9A (0.45) | SMN1; SMN2LMNAHTTRAB9ANPC1 | |
| SCHEMBL6437241 | 0.83 | RPA1 (0.64) | SMN1; SMN2LMNARAB9ANPC1HPGD | |
| SCHEMBL6353681 | 0.83 | KMT2A (0.64) | SMN1; SMN2LMNAHTTRAB9ANPC1 | |
| SCHEMBL6358855 | 0.81 | MAPT (0.57) | SMN1; SMN2LMNAHTTRAB9ANPC1 | |
| SCHEMBL6833850 | 0.81 | RAB9A (0.45) | SMN1; SMN2LMNAHTTRAB9ANPC1 | |
| SCHEMBL6351810 | 0.80 | KMT2A (0.52) | SMN1; SMN2LMNAHTTHPGDTSHR | |
| SCHEMBL6357750 | 0.79 | POLB (0.59) | SMN1; SMN2LMNAHTTRAB9ANPC1 | |
| SCHEMBL6830237 | 0.79 | RPA1 (0.47) | SMN1; SMN2HTTRAB9ANPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | SMN1; SMN2 2022/4885LMNA 3376/4885HTT 1599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.