SCHEMBL6833237

SCHEMBL6833237

Cc1c(S(=O)(=O)Nc2ccc3c(c2)OCCO3)csc1C(=O)Nc1ccc(Br)cc1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.45
LMNA P02545 5/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
NPC1 O15118 3/20 0.43
HPGD P15428 2/20 0.43
TP53 P04637 1/20 0.43
PKM P14618 1/20 0.43
NFKB1 P19838 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43
RPA1 P27694 2/20 0.43
GFER P55789 1/20 0.43
KMT2A Q03164 3/20 0.43
POLB P06746 1/20 0.43
EDNRB P24530 1/20 0.42
EDNRA P25101 1/20 0.42
HTT P42858 2/20 0.42
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
PTGES O14684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4097117 0.87 RPA1 (0.55) NPC1TP53RPA1GFERKMT2A
SCHEMBL6833850 0.84 RAB9A (0.45) RAB9ALMNASMN1; SMN2NPC1HPGD
SCHEMBL6830408 0.84 SMN1; SMN2 (0.48) RAB9ALMNASMN1; SMN2NPC1HPGD
SCHEMBL6437241 0.83 RPA1 (0.64) RAB9ALMNASMN1; SMN2NPC1HPGD
SCHEMBL6353696 0.83 PTGES (0.56) RAB9ALMNASMN1; SMN2NPC1HPGD
SCHEMBL6818216 0.83 MAPT (0.49) LMNARPA1GFERKMT2APOLB
SCHEMBL6818512 0.82 RPA1 (0.51) SMN1; SMN2HPGDTP53RPA1GFER
SCHEMBL6357750 0.81 POLB (0.59) RAB9ALMNASMN1; SMN2NPC1KMT2A
SCHEMBL6353699 0.80 RAB9A (0.56) RAB9ALMNASMN1; SMN2NPC1KMT2A
SCHEMBL6835804 0.80 RPA1 (0.46) RAB9ALMNASMN1; SMN2NPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040110802-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110802-A1 Antibacterial benzoic acid derivatives GABRD, GABBR1, GABRA1 RAB9A 4337/4885LMNA 3376/4885SMN1; SMN2 2022/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.