Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.39 |
| ▸ | TK1 | P04183 | 7/20 | 0.35 |
| ▸ | NT5M | Q9NPB1 | 1/20 | 0.35 |
| ▸ | TK2 | O00142 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3290516 | 0.87 | RNASE1 (0.43) | RNASE1TK1TK2 | |
| SCHEMBL2594578 | 0.84 | RNASE1 (0.42) | RNASE1TK1TK2 | |
| SCHEMBL2710682 | 0.84 | RNASE1 (0.42) | RNASE1 | |
| SCHEMBL6830778 | 0.83 | RNASE1 (0.36) | RNASE1TK1TK2 | |
| SCHEMBL6832147 | 0.83 | TK1 (0.47) | TK1 | |
| SCHEMBL6830123 | 0.82 | TOP2A (0.40) | RNASE1TK1TK2 | |
| SCHEMBL2034479 | 0.81 | RNASE1 (0.38) | RNASE1TK1TK2 | |
| SCHEMBL6830791 | 0.80 | NT5M (0.33) | RNASE1TK1NT5MTK2 | |
| SCHEMBL8027668 | 0.78 | RNASE1 (0.41) | RNASE1TK1TK2 | |
| SCHEMBL6830104 | 0.77 | TK1 (0.34) | RNASE1TK1TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743902-B1 | FOR USE IN ANTISENSE THERAPY FOR ENHANCING NUCLEASE RESISTANCE AND CELLULAR UPTAKE | VALEANT PHARMACEUTICALS INTERNATIONAL | 2004-06-01 | — | — | US | disclosed |