Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Proflavine SCHEMBL25348298 | 0.77 | LMNA (0.67) | MDM4NQO2LMNAMEN1KMT2A | |
| SCHEMBL11703495 | 0.77 | HTR3A (0.52) | MDM4NQO2LMNAMEN1KMT2A | |
| SCHEMBL29663215 | 0.76 | DHFR (0.49) | MDM4NQO2LMNAMEN1KMT2A | |
| SCHEMBL1118532 | 0.75 | ALDH1A1 (0.53) | NQO2LMNAKMT2ACHRM2ADRA2A | |
| SCHEMBL6639402 | 0.72 | POLB (0.61) | MDM4NQO2LMNAMEN1KMT2A | |
| SCHEMBL7469561 | 0.72 | ALDH1A1 (0.60) | MDM4NQO2LMNAMEN1KMT2A | |
| SCHEMBL8630481 | 0.72 | MDM4 (0.47) | MDM4LMNAMEN1KMT2AF2 | |
| SCHEMBL17066272 | 0.72 | MDM4 (0.61) | MDM4NQO2LMNAMEN1KMT2A | |
| SCHEMBL6094113 | 0.71 | DHFR (0.72) | MDM4LMNAMEN1KMT2AF2 | |
| SCHEMBL12774935 | 0.71 | ALDH1A1 (0.48) | LMNAMEN1KMT2AACHEHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015077550-A1 | ARYLQUINOLINE AND ANALOG COMPOUNDS AND USE THEREOF TO TREAT CANCER | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2015-05-28 | — | — | WO | claimed |
| WO-2015077550-A1 | ARYLQUINOLINE AND ANALOG COMPOUNDS AND USE THEREOF TO TREAT CANCER | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2015-05-28 | — | — | WO | disclosed |
| WO-2004087669-A1 | NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO. LTD. (JP) | 2004-10-14 | — | — | WO | disclosed |