Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.38 |
| ▸ | TK2 | O00142 | 9/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831414 | 1.00 | TK1 (0.38) | TK1TK2TYMP | |
| SCHEMBL7211237 | 0.85 | TK2 (0.35) | TK1TK2 | |
| SCHEMBL7206844 | 0.85 | TK2 (0.35) | TK1TK2 | |
| SCHEMBL7207527 | 0.85 | RNASE1 (0.34) | TK1TK2 | |
| SCHEMBL6830770 | 0.84 | TK2 (0.43) | TK1TK2TYMP | |
| SCHEMBL7995787 | 0.83 | TK1 (0.39) | TK1TK2TYMP | |
| SCHEMBL6827415 | 0.83 | TK2 (0.45) | TK1TK2 | |
| SCHEMBL7211272 | 0.83 | TK2 (0.34) | TK1TK2 | |
| SCHEMBL21626198 | 0.83 | TK2 (0.40) | TK1TK2TYMP | |
| SCHEMBL6323179 | 0.82 | TK2 (0.42) | TK1TK2TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082774-A1 | Novel phosphate and thiophosphate protecting groups | ISIS PHARMACEUTICALS, INC. | 2004-04-29 | — | — | US | disclosed |
| WO-2000055179-A1 | NOVEL PHOSPHATE AND THIOPHOSPHATE PROTECTING GROUPS | ISIS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082774-A1 | Novel phosphate and thiophosphate protecting groups | TYMP, MTAP, PPIP5K2 | TK1 27/4885TK2 116/4885TYMP 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.