Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28367828 | 0.87 | ALDH1A1 (0.53) | NCOA1NCOA3MAOAALDH1A1MAPT | |
| SCHEMBL144020 | 0.87 | NCOA1 (0.51) | NCOA1NCOA3MAOAALDH1A1MAPT | |
| SCHEMBL29726520 | 0.87 | NCOA1 (0.51) | NCOA1NCOA3MAOAALDH1A1MAPT | |
| SCHEMBL20339915 | 0.87 | NCOA1 (0.51) | NCOA1NCOA3MAOAALDH1A1MAPT | |
| SCHEMBL9418327 | 0.86 | MAOA (0.53) | NCOA1NCOA3MAOAALDH1A1MAPT | |
| SCHEMBL8541042 | 0.81 | ALDH1A1 (0.47) | NCOA1NCOA3MAOAALDH1A1MAPT | |
| SCHEMBL1501443 | 0.81 | NCOA1 (0.50) | NCOA1NCOA3MAOAALDH1A1MAPT | |
| SCHEMBL8537051 | 0.81 | MAPT (0.50) | NCOA1NCOA3MAOAALDH1A1MAPT | |
| SCHEMBL1851072 | 0.81 | ALDH1A1 (0.56) | NCOA1NCOA3MAOAALDH1A1MAPT | |
| SCHEMBL8542704 | 0.80 | MAOA (0.52) | NCOA1NCOA3MAOAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6747170-B2 | LEUCO DYES; MOLECULE HAVING AT LEAST TWO AROMATIC RINGS, TWO CARBOXYL GROUPS, AND EITHER TWO AMIDES OR TWO ESTERS; PRESERVATION STABILITY | RICOH COMPANY, LTD. (JP) | 2004-06-08 | — | — | US | disclosed |
| US-20040071187-A1 | Thermosensitive recording material and color developer compound therefor | HAYAKAWA KUNIO (JP) | 2004-04-15 | — | — | US | disclosed |
| US-6180560-B1 | LEUCO DYE AND DYE DEVELOPER OF AROMATIC AMIDE OR ESTER; PRESERVATION STABILITY | RICOH COMPANY, LTD. (JP) | 2001-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040071187-A1 | Thermosensitive recording material and color developer compound therefor | LRBA, THEM6, GOT1 | NCOA1 820/4885NCOA3 1283/4885MAOA 1116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.