SCHEMBL6832673

SCHEMBL6832673

CCN(CC)c1ccc2c(c1)C(=O)OC2(N(C)c1ccc(C)cc1)N(C)c1ccc(C)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.43
MEN1 O00255 7/20 0.43
KMT2A Q03164 7/20 0.43
HPGD P15428 5/20 0.43
HSD17B10 Q99714 4/20 0.43
L3MBTL1 Q9Y468 4/20 0.43
MAPK1 P28482 3/20 0.43
MAPT P10636 3/20 0.43
TDP1 Q9NUW8 3/20 0.42
CYP3A4 P08684 2/20 0.42
HIF1A Q16665 2/20 0.42
PKM P14618 1/20 0.37
CYP19A1 P11511 1/20 0.37
RPS6KA2 Q15349 1/20 0.37
CASP1 P29466 3/20 0.36
CASP7 P55210 3/20 0.36
GLA P06280 2/20 0.36
IGLV6-57 P01721 1/20 0.36
ATM Q13315 1/20 0.36
KDM4E B2RXH2 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6834819 0.87 ALDH1A1 (0.56) ALDH1A1MEN1KMT2AHPGDHSD17B10
SCHEMBL4615007 0.82 MEN1 (0.55) ALDH1A1MEN1KMT2AHPGDHSD17B10
SCHEMBL6832708 0.82 ALDH1A1 (0.44) ALDH1A1MEN1KMT2AHPGDHSD17B10
SCHEMBL6829601 0.79 NPSR1 (0.43) ALDH1A1MEN1KMT2AHPGDHSD17B10
SCHEMBL312376 0.76 ALDH1A1 (0.56) ALDH1A1MEN1KMT2AHPGDHSD17B10
SCHEMBL29671371 0.76 ALDH1A1 (0.56) ALDH1A1MEN1KMT2AHPGDHSD17B10
SCHEMBL10349121 0.75 ALDH1A1 (0.66) ALDH1A1MEN1KMT2AHPGDHSD17B10
SCHEMBL10349246 0.75 ALDH1A1 (0.66) ALDH1A1MEN1KMT2AHPGDHSD17B10
SCHEMBL10349315 0.75 ALDH1A1 (0.66) ALDH1A1MEN1KMT2AHPGDHSD17B10
SCHEMBL5188731 0.75 ALDH1A1 (0.66) ALDH1A1MEN1KMT2AHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6747170-B2 LEUCO DYES; MOLECULE HAVING AT LEAST TWO AROMATIC RINGS, TWO CARBOXYL GROUPS, AND EITHER TWO AMIDES OR TWO ESTERS; PRESERVATION STABILITY RICOH COMPANY, LTD. (JP) 2004-06-08 US disclosed
US-20040071187-A1 Thermosensitive recording material and color developer compound therefor HAYAKAWA KUNIO (JP) 2004-04-15 US disclosed
US-6555705-B1 A supported thermosensitive recording layer containing a leuco dye and a color developer to induce color in the leuco dye upon heating; using 4-(2- or 4-phenoxyethoxy- or butoxy phthalic acid; image stability; oil, fat repellant RICOH COMPANY, LTD. (JP) 2003-04-29 US disclosed
US-6180560-B1 LEUCO DYE AND DYE DEVELOPER OF AROMATIC AMIDE OR ESTER; PRESERVATION STABILITY RICOH COMPANY, LTD. (JP) 2001-01-30 US disclosed
US-5583088-A ELECTRON DONOR, ELECTRON ACCEPTOR, DECOLORIZATION PROMOTER AGENT, BINDER RESIN RICOH COMPANY, LTD. (JP) 1996-12-10 US disclosed
EP-0612628-B1 Thermosensitive recording material using phthalic acid derivatives RICOH KK (JP) 1996-07-10 EP disclosed
US-5482912-A DEVELOPERS, THERMAL PRINTING, INTERMEDIATE LAYER OF THERMOPLASTIC HOLLOW SPHERES RICOH COMPANY, LTD. (JP) 1996-01-09 US disclosed
EP-0612628-A1 Thermosensitive recording material using phthalic acid derivatives Ricoh Company, Ltd (JP) 1994-08-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040071187-A1 Thermosensitive recording material and color developer compound therefor LRBA, THEM6, GOT1 ALDH1A1 274/4885MEN1 3457/4885KMT2A 1691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.