SCHEMBL6829601

SCHEMBL6829601

Cc1ccc(N(C)C2(N(C)c3ccc(C)cc3)OC(=O)c3ccccc32)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 6/20 0.43
LMNA P02545 4/20 0.43
CFTR P13569 1/20 0.40
GOPC Q9HD26 1/20 0.40
CES1 P23141 1/20 0.40
MAPT P10636 4/20 0.38
POLB P06746 3/20 0.38
GPR55 Q9Y2T6 2/20 0.38
ALOX12 P18054 1/20 0.38
TDP1 Q9NUW8 4/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
NTSR2 O95665 1/20 0.38
NTSR1 P30989 1/20 0.38
CYP3A4 P08684 4/20 0.37
CYP2C19 P33261 3/20 0.37
HTT P42858 2/20 0.37
CYP1A2 P05177 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6834819 0.84 ALDH1A1 (0.56) NPSR1LMNACES1MAPTPOLB
SCHEMBL4615007 0.81 MEN1 (0.55) NPSR1LMNACES1POLBGPR55
SCHEMBL6832708 0.81 ALDH1A1 (0.44) NPSR1LMNACES1MAPTPOLB
SCHEMBL4577226 0.79 CFTR (0.50) NPSR1LMNACFTRGOPCMAPT
SCHEMBL6832673 0.79 ALDH1A1 (0.43) NPSR1LMNAMAPTTDP1MEN1
SCHEMBL6833100 0.74 LMNA (0.36) NPSR1LMNACFTRGOPCCES1
SCHEMBL4632521 0.70 SMN1; SMN2 (0.46) NPSR1LMNACFTRGOPCMAPT
SCHEMBL822834 0.70 CFTR (0.73) NPSR1LMNACFTRGOPCMAPT
SCHEMBL7850945 0.69 NPSR1 (0.50) NPSR1LMNACFTRGOPCMAPT
SCHEMBL9787743 0.67 CFTR (0.57) NPSR1LMNACFTRGOPCMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7316096-A None JP disclosed
US-6747170-B2 LEUCO DYES; MOLECULE HAVING AT LEAST TWO AROMATIC RINGS, TWO CARBOXYL GROUPS, AND EITHER TWO AMIDES OR TWO ESTERS; PRESERVATION STABILITY RICOH COMPANY, LTD. (JP) 2004-06-08 US disclosed
US-20040071187-A1 Thermosensitive recording material and color developer compound therefor HAYAKAWA KUNIO (JP) 2004-04-15 US disclosed
US-6555705-B1 A supported thermosensitive recording layer containing a leuco dye and a color developer to induce color in the leuco dye upon heating; using 4-(2- or 4-phenoxyethoxy- or butoxy phthalic acid; image stability; oil, fat repellant RICOH COMPANY, LTD. (JP) 2003-04-29 US disclosed
US-6180560-B1 LEUCO DYE AND DYE DEVELOPER OF AROMATIC AMIDE OR ESTER; PRESERVATION STABILITY RICOH COMPANY, LTD. (JP) 2001-01-30 US disclosed
US-5583088-A ELECTRON DONOR, ELECTRON ACCEPTOR, DECOLORIZATION PROMOTER AGENT, BINDER RESIN RICOH COMPANY, LTD. (JP) 1996-12-10 US disclosed
EP-0612628-B1 Thermosensitive recording material using phthalic acid derivatives RICOH KK (JP) 1996-07-10 EP disclosed
US-5482912-A DEVELOPERS, THERMAL PRINTING, INTERMEDIATE LAYER OF THERMOPLASTIC HOLLOW SPHERES RICOH COMPANY, LTD. (JP) 1996-01-09 US disclosed
JP-H07316096-A HEAT-SENSITIVE RECORDING MATERIAL AND NEW PHTHALIC ACID DERIVATIVE USED THEREFOR RICOH CO LTD 1995-12-05 JP disclosed
EP-0612628-A1 Thermosensitive recording material using phthalic acid derivatives Ricoh Company, Ltd (JP) 1994-08-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040071187-A1 Thermosensitive recording material and color developer compound therefor LRBA, THEM6, GOT1 NPSR1 2751/4885LMNA 2817/4885CFTR 4202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.