Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | PPOX | P50336 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6834819 | 0.86 | ALDH1A1 (0.56) | ALDH1A1CYP3A4HPGDHIF1AHSD17B10 | |
| SCHEMBL4615007 | 0.84 | MEN1 (0.55) | ALDH1A1CYP3A4HPGDHIF1AHSD17B10 | |
| SCHEMBL6832673 | 0.82 | ALDH1A1 (0.43) | ALDH1A1CYP3A4HPGDHIF1AHSD17B10 | |
| SCHEMBL6829601 | 0.81 | NPSR1 (0.43) | ALDH1A1CYP3A4HPGDHIF1AHSD17B10 | |
| SCHEMBL221163 | 0.72 | TDP1 (0.81) | ALDH1A1CYP3A4HPGDHIF1AHSD17B10 | |
| SCHEMBL10933724 | 0.70 | ALDH1A1 (0.65) | ALDH1A1CYP3A4HPGDHIF1AHSD17B10 | |
| SCHEMBL12726666 | 0.69 | TDP1 (0.79) | ALDH1A1CYP3A4HPGDHIF1AHSD17B10 | |
| SCHEMBL12152338 | 0.67 | ALDH1A1 (0.81) | ALDH1A1CYP3A4HPGDHIF1AHSD17B10 | |
| SCHEMBL1892014 | 0.67 | ALDH1A1 (0.59) | ALDH1A1CYP3A4HPGDHIF1AHSD17B10 | |
| SCHEMBL5143698 | 0.66 | ALDH1A1 (0.66) | ALDH1A1CYP3A4HPGDHIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6747170-B2 | LEUCO DYES; MOLECULE HAVING AT LEAST TWO AROMATIC RINGS, TWO CARBOXYL GROUPS, AND EITHER TWO AMIDES OR TWO ESTERS; PRESERVATION STABILITY | RICOH COMPANY, LTD. (JP) | 2004-06-08 | — | — | US | disclosed |
| US-20040071187-A1 | Thermosensitive recording material and color developer compound therefor | HAYAKAWA KUNIO (JP) | 2004-04-15 | — | — | US | disclosed |
| US-6555705-B1 | A supported thermosensitive recording layer containing a leuco dye and a color developer to induce color in the leuco dye upon heating; using 4-(2- or 4-phenoxyethoxy- or butoxy phthalic acid; image stability; oil, fat repellant | RICOH COMPANY, LTD. (JP) | 2003-04-29 | — | — | US | disclosed |
| US-6180560-B1 | LEUCO DYE AND DYE DEVELOPER OF AROMATIC AMIDE OR ESTER; PRESERVATION STABILITY | RICOH COMPANY, LTD. (JP) | 2001-01-30 | — | — | US | disclosed |
| US-5583088-A | ELECTRON DONOR, ELECTRON ACCEPTOR, DECOLORIZATION PROMOTER AGENT, BINDER RESIN | RICOH COMPANY, LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| EP-0612628-B1 | Thermosensitive recording material using phthalic acid derivatives | RICOH KK (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5482912-A | DEVELOPERS, THERMAL PRINTING, INTERMEDIATE LAYER OF THERMOPLASTIC HOLLOW SPHERES | RICOH COMPANY, LTD. (JP) | 1996-01-09 | — | — | US | disclosed |
| EP-0612628-A1 | Thermosensitive recording material using phthalic acid derivatives | Ricoh Company, Ltd (JP) | 1994-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040071187-A1 | Thermosensitive recording material and color developer compound therefor | LRBA, THEM6, GOT1 | ALDH1A1 274/4885CYP3A4 647/4885HPGD 1896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.