Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.37 |
| ▸ | PDE6D | O43924 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 3/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 3/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7489996 | 0.85 | NPY1R (0.40) | HTR4NPY1RGABRA1GABRG2GABRB3 | |
| SCHEMBL6838078 | 0.85 | MERTK (0.43) | HTR4NPY1RGABRA1GABRG2GABRB3 | |
| SCHEMBL6928192 | 0.85 | HTR4 (0.42) | HTR4NPY1RGABRA1GABRG2GABRB3 | |
| SCHEMBL6834046 | 0.85 | PTGER4 (0.36) | CTSSCTSKTLR7 | |
| SCHEMBL6929281 | 0.85 | NPY1R (0.40) | HTR4NPY1RGABRA1GABRG2GABRB3 | |
| SCHEMBL6925914 | 0.85 | NPY1R (0.44) | HTR4NPY1RGABRA1GABRG2GABRB3 | |
| SCHEMBL6838557 | 0.84 | MAOB (0.39) | HTR4NPY1RGABRA1GABRG2GABRB3 | |
| Hydrochloric Acid SCHEMBL6923145 | 0.84 | NPY1R (0.43) | HTR4NPY1RGABRA1GABRG2GABRB3 | |
| SCHEMBL6833713 | 0.83 | NPY1R (0.39) | HTR4NPY1RGABRA1GABRG2GABRB3 | |
| SCHEMBL6838636 | 0.83 | PTGER4 (0.41) | HTR4NPY1RGABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040054182-A1 | 1h-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2004-03-18 | — | — | US | disclosed |
| EP-1256582-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2002-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040054182-A1 | 1h-imidazopyridine derivatives | IL2, IL1A, IL4 | HTR4 2764/4885NPY1R 1070/4885GABRA1 728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.