Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.52 |
| ▸ | IDH1 | O75874 | 9/20 | 0.51 |
| ▸ | RPA1 | P27694 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | SLC10A6 | Q3KNW5 | 2/20 | 0.48 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.48 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6833646 | 0.90 | RPA1 (0.51) | METAP2IDH1RPA1GFERSLC10A6 | |
| SCHEMBL6833850 | 0.84 | RAB9A (0.45) | IDH1RPA1GFERMEN1KMT2A | |
| SCHEMBL6835657 | 0.84 | LMNA (0.48) | METAP2RPA1GFERPTGESALOX5 | |
| SCHEMBL6835788 | 0.83 | METAP2 (0.45) | METAP2IDH1SLC10A6SLC10A2SLC10A1 | |
| SCHEMBL6833981 | 0.83 | RPA1 (0.43) | METAP2RPA1GFERPTGESALOX5 | |
| SCHEMBL6834271 | 0.79 | MEN1 (0.49) | METAP2MEN1KMT2ALMNAMAPT | |
| SCHEMBL6352359 | 0.78 | METAP2 (0.71) | METAP2RPA1GFERSLC10A6SLC10A2 | |
| SCHEMBL6359200 | 0.77 | MAPT (0.65) | METAP2RPA1GFERPTGESALOX5 | |
| SCHEMBL6830627 | 0.77 | CPT1A (0.46) | MEN1KMT2A | |
| SCHEMBL6833903 | 0.77 | MEN1 (0.42) | METAP2RPA1GFERMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | METAP2 3959/4885IDH1 4018/4885RPA1 3767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.