Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 7/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 8/20 | 0.45 |
| ▸ | PPARD | Q03181 | 8/20 | 0.45 |
| ▸ | PPARA | Q07869 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7069536 | 0.89 | PTPRC (0.41) | PPARGPPARDPPARASLC16A1 | |
| SCHEMBL6830878 | 0.89 | AKR1C2 (0.47) | AKR1C4AKR1C3AKR1C2AKR1C1ALB | |
| SCHEMBL6834074 | 0.86 | ALB (0.44) | ALBPPARGPPARDPPARASLC16A1 | |
| SCHEMBL6711949 | 0.83 | GRM4 (0.36) | PPARGPPARDPPARA | |
| SCHEMBL6708841 | 0.81 | GRIK1 (0.40) | — | |
| SCHEMBL6830542 | 0.79 | GRM4 (0.55) | AKR1C4AKR1C3AKR1C2AKR1C1SERPINE1 | |
| SCHEMBL6835794 | 0.77 | NHERF1 (0.53) | AKR1C4AKR1C3AKR1C2AKR1C1SERPINE1 | |
| SCHEMBL6711677 | 0.74 | HIF1A (0.40) | PPARGPPARDPPARA | |
| SCHEMBL417998 | 0.73 | SERPINE1 (0.61) | SERPINE1KDM4EHSD17B10 | |
| SCHEMBL6711652 | 0.72 | FBP1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | claimed |
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | AKR1C4 2813/4885AKR1C3 2981/4885AKR1C2 2596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.