Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 4/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711677 | 0.88 | HIF1A (0.40) | FBP1NAMPTKMT2ALMNA | |
| SCHEMBL6711949 | 0.88 | GRM4 (0.36) | FBP1F10NAMPTPTGDR2 | |
| SCHEMBL6710210 | 0.86 | GSK3A (0.36) | F10TRPA1KMT2APTGDR2 | |
| SCHEMBL6710104 | 0.85 | TRPA1 (0.33) | FBP1TRPA1KMT2ALMNAROCK2 | |
| SCHEMBL6711936 | 0.85 | FEN1 (0.34) | FBP1F10TRPA1NAMPTPTGDR2 | |
| SCHEMBL6713833 | 0.85 | CXCR1 (0.34) | TRPA1KMT2ALMNAROCK2 | |
| SCHEMBL6709087 | 0.84 | TRPA1 (0.42) | TRPA1KMT2ALMNAROCK2 | |
| SCHEMBL6708989 | 0.84 | LMNA (0.38) | TRPA1KMT2ALMNAROCK2MAPK14 | |
| SCHEMBL6710384 | 0.84 | F10 (0.33) | FBP1F10SIRT2 | |
| SCHEMBL6711902 | 0.83 | THRB (0.37) | F10TRPA1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | FBP1 1709/4885F10 2246/4885TRPA1 594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.