Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CCKAR | P32238 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6833975 | 0.92 | MAPK1 (0.42) | MAPTMAPK1TDP1KDM4ECCKAR | |
| SCHEMBL6833233 | 0.89 | MAPT (0.42) | MAPTMAPK1TDP1ALDH1A1POLB | |
| SCHEMBL6833939 | 0.87 | L3MBTL1 (0.48) | MAPTMAPK1TDP1ALDH1A1ALB | |
| SCHEMBL6830151 | 0.87 | ALB (0.42) | MAPTMAPK1TDP1CCKARALB | |
| SCHEMBL6835677 | 0.86 | CCKAR (0.41) | MAPTMAPK1TDP1CCKARALB | |
| SCHEMBL6833137 | 0.86 | MAP3K5 (0.44) | KDM4ECCKARALBPOLBNR1H4 | |
| SCHEMBL6833910 | 0.85 | KDM4E (0.45) | MAPTMAPK1TDP1KDM4EALDH1A1 | |
| SCHEMBL6834154 | 0.85 | KMT2A (0.49) | MAPTTDP1RAB9AALBNR1H4 | |
| SCHEMBL6835693 | 0.84 | POLB (0.47) | KDM4EALDH1A1ALBPOLBRXFP1 | |
| SCHEMBL6833081 | 0.84 | NHERF1 (0.41) | CCKARALBNR1H4NSD2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | claimed |
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | MAPT 4759/4885MAPK1 2575/4885TDP1 2738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.