Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.48 |
| ▸ | RPA1 | P27694 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.45 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6833786 | 0.88 | GRM5 (0.55) | MAPTKMT2AMEN1POLBSTING1 | |
| SCHEMBL6834198 | 0.83 | ALDH1A1 (0.54) | MAPTKMT2AMEN1POLBGRM5 | |
| SCHEMBL6813769 | 0.79 | MEN1 (0.74) | MAPTKMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL6349859 | 0.78 | MAPT (0.76) | MAPTKMT2AMEN1AKR1C2AKR1C1 | |
| SCHEMBL6833263 | 0.73 | HDAC6 (0.51) | MAPTKMT2AMEN1POLBSTING1 | |
| SCHEMBL6834328 | 0.73 | AKR1C2 (0.48) | KMT2AMEN1POLBAKR1C2AKR1C1 | |
| SCHEMBL6359832 | 0.73 | MAPT (0.57) | MAPTKMT2AMEN1POLBAKR1C2 | |
| SCHEMBL6349807 | 0.73 | AKR1C2 (0.63) | MAPTKMT2AMEN1AKR1C2AKR1C1 | |
| SCHEMBL4689569 | 0.72 | RPA1 (0.48) | RPA1KMT2AMEN1SMPD1GRM5 | |
| SCHEMBL6834063 | 0.71 | AKR1C2 (0.46) | MAPTKMT2AMEN1POLBSTING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | CHRNB2 4880/4885CHRNA4 4871/4885RPA1 3767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.