Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.48 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6834198 | 0.90 | ALDH1A1 (0.54) | GRM5MAPTNPC1HPGDNFKB1 | |
| SCHEMBL6834032 | 0.88 | CHRNB2 (0.48) | GRM5AKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL6834328 | 0.80 | AKR1C2 (0.48) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL6834037 | 0.80 | PHGDH (0.52) | AKR1C2AKR1C1AKR1C4AKR1C3STING1 | |
| SCHEMBL28952698 | 0.77 | SMPD1 (0.62) | GRM5MMETRPV4 | |
| SCHEMBL6834682 | 0.75 | SORT1 (0.60) | GRM5AKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL6813965 | 0.75 | MEN1 (0.72) | AKR1C2AKR1C1AKR1C4AKR1C3MAPT | |
| SCHEMBL570061 | 0.74 | RPA1 (0.63) | GRM5MAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6353351 | 0.74 | SERPINE1 (0.71) | AKR1C2AKR1C1AKR1C4AKR1C3TRPM2 | |
| SCHEMBL2552942 | 0.73 | GRM5 (0.61) | GRM5MEN1KMT2AMMETRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | GRM5 4081/4885AKR1C2 2596/4885AKR1C1 2161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.