Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 3/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7188395 | 0.85 | PTGER1 (0.39) | AKR1C2AKR1C1CA2CA9MEN1 | |
| SCHEMBL6834328 | 0.82 | AKR1C2 (0.48) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL7188389 | 0.79 | LRRK2 (0.36) | PTGER1CYP1A2POLBMAPTGAA | |
| SCHEMBL17611006 | 0.78 | P2RY14 (0.52) | MEN1KMT2APTGER1CYP1A2POLB | |
| SCHEMBL6833786 | 0.73 | GRM5 (0.55) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL6821934 | 0.72 | AKR1C2 (0.53) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL6834682 | 0.71 | SORT1 (0.60) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL6834032 | 0.71 | CHRNB2 (0.48) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL17610977 | 0.71 | SMN1; SMN2 (0.56) | KMT2APOLBMAPTGAA | |
| SCHEMBL6833266 | 0.70 | STING1 (0.50) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | AKR1C2 2596/4885AKR1C1 2161/4885CA2 2212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.