Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | METAP2 | P50579 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 6/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6835806 | 0.84 | POLB (0.45) | POLBAKR1C2AKR1C1CA12CA9 | |
| SCHEMBL6834402 | 0.81 | AKR1C2 (0.47) | POLBAKR1C2AKR1C1KDM4ETDP1 | |
| SCHEMBL6834406 | 0.81 | ALDH1A1 (0.44) | POLBAKR1C2AKR1C1METAP2KDM4E | |
| SCHEMBL6830522 | 0.79 | CA12 (0.44) | POLBAKR1C2AKR1C1CA12CA9 | |
| SCHEMBL6833867 | 0.75 | METAP2 (0.52) | METAP2KDM4E | |
| SCHEMBL6833646 | 0.74 | RPA1 (0.51) | AKR1C2AKR1C1METAP2 | |
| SCHEMBL6833903 | 0.73 | MEN1 (0.42) | POLBAKR1C2AKR1C1METAP2TDP1 | |
| SCHEMBL6833913 | 0.72 | ALB (0.38) | POLBPLK1CYP2C9PLK3 | |
| SCHEMBL6833981 | 0.72 | RPA1 (0.43) | POLBAKR1C2AKR1C1METAP2 | |
| SCHEMBL6835788 | 0.72 | METAP2 (0.45) | POLBAKR1C2AKR1C1METAP2AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | POLB 637/4885AKR1C2 2596/4885AKR1C1 2161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.