SCHEMBL6835688

SCHEMBL6835688

N#Cc1ccc(NC(=O)c2cc3cccc(NC(=O)c4ccccc4O)c3[nH]2)c(C(=O)O)c1

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.45
NR1H4 Q96RI1 1/20 0.45
RXFP1 Q9HBX9 2/20 0.44
NHERF1 O14745 1/20 0.44
HTT P42858 2/20 0.43
CCKAR P32238 1/20 0.42
ALB P02768 1/20 0.42
NPC1 O15118 1/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
GAA P10253 1/20 0.41
NSD2 O96028 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6834154 0.90 KMT2A (0.49) NR1H4RXFP1NHERF1ALBNPC1
SCHEMBL6835708 0.88 CCKAR (0.51) NHERF1CCKARNPC1LMNA
SCHEMBL6834385 0.87 SERPINE1 (0.51) NR1H4RXFP1NHERF1ALBNPC1
SCHEMBL6833137 0.87 MAP3K5 (0.44) NR1H4RXFP1NHERF1CCKARALB
SCHEMBL6834115 0.86 ALB (0.47) GFERNR1H4RXFP1ALB
SCHEMBL6813569 0.86 CCKAR (0.45) NR1H4RXFP1HTTCCKAR
SCHEMBL6830877 0.85 AKR1C2 (0.48) NR1H4RXFP1NHERF1ALB
SCHEMBL6834504 0.85 LMNA (0.47) RXFP1NHERF1CCKARALBLMNA
SCHEMBL6833897 0.85 ALB (0.42) NR1H4RXFP1NHERF1ALBNSD2
SCHEMBL6830151 0.85 ALB (0.42) NR1H4RXFP1NHERF1CCKARALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040110802-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-06-10 US claimed
US-20040110802-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110802-A1 Antibacterial benzoic acid derivatives GABRD, GABBR1, GABRA1 GFER 900/4885NR1H4 1201/4885RXFP1 3523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.