Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA1 | P56199 | 2/20 | 0.65 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TCF4 | P15884 | 2/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6834616 | 0.96 | ITGA1 (0.68) | ITGA1HSD17B2MAPTSMN1; SMN2POLB | |
| SCHEMBL6834341 | 0.96 | ITGA1 (0.68) | ITGA1HSD17B2MAPTSMN1; SMN2POLB | |
| SCHEMBL6834344 | 0.96 | ITGA1 (0.68) | ITGA1HSD17B2MAPTSMN1; SMN2POLB | |
| SCHEMBL6833538 | 0.86 | ITGA1 (0.54) | ITGA1MAPTSMN1; SMN2POLBHDAC2 | |
| SCHEMBL6833536 | 0.86 | ITGA1 (0.54) | ITGA1MAPTSMN1; SMN2POLBHDAC2 | |
| SCHEMBL6834493 | 0.86 | TCF4 (0.69) | MAPTSMN1; SMN2HDAC2HDAC8HDAC6 | |
| SCHEMBL6834188 | 0.84 | HDAC1 (0.60) | ITGA1MAPTSMN1; SMN2POLBHDAC2 | |
| SCHEMBL6834529 | 0.83 | TCF4 (0.65) | ITGA1MAPTSMN1; SMN2HDAC2HDAC8 | |
| SCHEMBL6834490 | 0.83 | TCF4 (0.65) | ITGA1MAPTSMN1; SMN2HDAC2HDAC8 | |
| SCHEMBL6834660 | 0.83 | LMNA (0.58) | ITGA1SMN1; SMN2POLBHDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040029928-A1 | Novel propenohydroxamic acid derivatives | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-12 | — | — | US | disclosed |
| EP-1314721-A1 | NOVEL PROPENOHYDROXAMIC ACID DERIVATIVES | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029928-A1 | Novel propenohydroxamic acid derivatives | TNF, SI, HDGF | ITGA1 871/4885HSD17B2 505/4885MAPT 4627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.