Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 4/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17013844 | 0.86 | ALDH1A1 (0.47) | LIPGALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL17013838 | 0.82 | CYP1A2 (0.48) | LIPGALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6834417 | 0.81 | L3MBTL1 (0.43) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL976168 | 0.80 | LIPG (0.40) | LIPGKMT2ABCHEACHE | |
| SCHEMBL1506800 | 0.80 | APP (0.35) | ALDH1A1KDM4ELMNAGAAL3MBTL1 | |
| SCHEMBL20926054 | 0.78 | MAPT (0.36) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4460221 | 0.77 | CYP2D6 (0.50) | LIPGCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1506801 | 0.77 | ALDH1A1 (0.39) | LIPGALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3292925 | 0.75 | KDM4E (0.42) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL15586613 | 0.73 | NQO2 (0.44) | KDM4EBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6804544-B2 | GLUCOSE MEASUREMENT | MINIMED, INC. | 2004-10-12 | — | — | US | disclosed |
| EP-0862648-B1 | DETECTION OF BIOLOGICAL MOLECULES USING CHEMICAL AMPLIFICATION AND OPTICAL SENSORS | MEDTRONIC MINIMED INC (US) | 2004-10-06 | — | — | EP | disclosed |
| US-6750311-B1 | CONCENTRATION OF BLOOD GLUCOSE; BORONATE COMPLEX WITH A FLUORESCENT DYE; POLYURETHANE OR POLYUREA BIOCOMPATABLE MATRIX BY REACTION OF A DIISOCYANATE WITH A POLYMERIC DIOL OR POLYMERIC DIAMINE | MINIMED INC. | 2004-06-15 | — | — | US | disclosed |
| US-20020018843-A1 | Detection of biological molecules using chemical amplification and optical sensors | MINIMED INC. | 2002-02-14 | — | — | US | disclosed |
| US-6319540-B1 | IMMOBILIZING BORONIC ACID MOIETY IN SOLID SUPPORT BY ATTACHING TO A POLYMER MATRIX | MINIMED INC. | 2001-11-20 | — | — | US | disclosed |
| US-6011984-A | Detection of biological molecules using chemical amplification and optical sensors | MINIMED INC. (US) | 2000-01-04 | — | — | US | disclosed |
| US-6002954-A | IMPLANTABLE AMPLIFICATION SYSTEM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-12-14 | — | — | US | disclosed |
| EP-0862648-A1 | DETECTION OF BIOLOGICAL MOLECULES USING CHEMICAL AMPLIFICATION AND OPTICAL SENSORS | Minimed Inc. (US) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997019188-A1 | DETECTION OF BIOLOGICAL MOLECULES USING CHEMICAL AMPLIFICATION AND OPTICAL SENSORS | MINIMED, INC. (US) | 1997-05-29 | — | — | WO | disclosed |