Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 9/20 | 0.34 |
| ▸ | CTSB | P07858 | 7/20 | 0.34 |
| ▸ | CTSK | P43235 | 7/20 | 0.34 |
| ▸ | CTSL | P07711 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6836868 | 0.93 | CTSL (0.36) | HPGDPOLBCTSSCTSBCTSK | |
| SCHEMBL7685576 | 0.91 | CTSL (0.38) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6837095 | 0.87 | CTSL (0.37) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6832858 | 0.86 | CTSL (0.37) | CTSSCTSBCTSKCTSLALDH1A1 | |
| SCHEMBL6832872 | 0.86 | CTSL (0.39) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6836041 | 0.85 | CTSS (0.42) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6836712 | 0.85 | CTSL (0.38) | HPGDPOLBCTSSCTSBCTSK | |
| SCHEMBL6836731 | 0.84 | CTSL (0.39) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6346166 | 0.83 | CTSS (0.36) | HPGDPOLBCTSSCTSBCTSK | |
| SCHEMBL6836067 | 0.83 | CTSK (0.39) | CTSSCTSBCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040006078-A1 | Compounds useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2004-01-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006078-A1 | Compounds useful as reversible inhibitors of cysteine proteases | CTSS, CTSK, CTSB | HPGD 1053/4885POLB 2468/4885CTSS 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.